PCNA staining has numerous applications in both research and clinical settings:
Cancer Research: PCNA staining is commonly used to assess tumor proliferation rates, helping in the diagnosis and prognosis of various cancers. Developmental Biology: It is used to study cell proliferation during embryonic development. Neuroscience: PCNA staining helps in understanding neurogenesis and brain development. Regenerative Medicine: It is employed to evaluate the efficiency of tissue regeneration. Toxicology: PCNA staining can be used to assess the effects of toxic substances on cell proliferation.