What Role Do Glial Cells Play in Psychiatric Disorders?
Glial cells are non-neuronal cells in the central nervous system that provide support and protection for neurons. In psychiatric disorders, glial cells, including astrocytes, oligodendrocytes, and microglia, often exhibit significant changes. For example, in depression, a reduction in astrocyte density is commonly observed, which can affect neurotransmitter regulation and synaptic function. Similarly, alterations in oligodendrocytes can impact myelination, while microglial activation is frequently associated with neuroinflammation in various psychiatric conditions.
