What Histological Changes Occur in Common Kidney Diseases?
Various kidney diseases manifest distinct histological changes. In glomerulonephritis, inflammation of the glomeruli leads to hypercellularity and basement membrane thickening. Diabetic nephropathy is characterized by glomerulosclerosis, mesangial expansion, and thickened basement membranes. In acute tubular necrosis, tubular epithelial cells show necrosis and loss of brush borders. Interstitial fibrosis and tubular atrophy are common in chronic kidney disease, reflecting long-term damage.
