How do MHC Class II Molecules Differ from MHC Class I Molecules?
While both MHC Class I and Class II molecules serve to present antigens, they differ in their sources of antigens and the types of T cells they interact with. MHC Class I molecules present endogenous antigens (derived from within the cell) to [CD8+ T cells](), or cytotoxic T cells, whereas MHC Class II molecules present exogenous antigens (derived from outside the cell) to CD4+ T cells.
