Failure of lubrication can lead to various pathological conditions. For instance: - Osteoarthritis: A condition where the synovial fluid is insufficient or of poor quality, leading to increased friction and wear of articular cartilage. - Dry Eye Syndrome: Inadequate production of tears (a form of lubrication) can cause irritation and damage to the ocular surface. - Dry Mouth (Xerostomia): Lack of saliva can lead to difficulty in swallowing, speaking, and increased dental issues.