Enzymatic Activity: It catalyzes the conversion of NAD+ into ADP-ribose, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate (NAADP), which are important for intracellular calcium signaling. Signal Transduction: CD38 participates in various signaling pathways, influencing cell proliferation, differentiation, and apoptosis. Cell Adhesion: It facilitates cell-cell interactions, particularly in the immune system, aiding in immune responses.