Handling human and animal tissues in an ethical manner is a cornerstone of histological research. For human tissues, obtaining informed consent is mandatory. Researchers must ensure that donors are fully aware of how their tissues will be used and that they agree to it without any coercion.
For animal tissues, ethical integrity involves adhering to the principles of 3Rs: Replacement, Reduction, and Refinement. Researchers should seek alternatives to animal use, minimize the number of animals used, and refine procedures to cause the least harm and distress.
