What Is the Role of Immunohistochemistry (IHC) in Hematopathology?
Immunohistochemistry (IHC) is vital for the diagnosis and classification of hematological malignancies. IHC involves using antibodies to detect specific proteins (antigens) in tissue sections. This technique helps differentiate between various types of lymphomas and leukemias by identifying unique markers on the surface or inside cells. For example, CD20 is a marker for B-cell lymphomas, while CD3 is used for T-cell lymphomas.
