central pallor

What Does Abnormal Central Pallor Indicate?

Abnormal central pallor can be indicative of various hematological conditions:
Hypochromic anemia: Increased central pallor is often seen in conditions where there is a deficiency in hemoglobin, such as iron deficiency anemia.
Spherocytosis: Decreased or absent central pallor can be observed in hereditary spherocytosis, where RBCs lose their biconcave shape and become more spherical.
Microcytic anemia: In conditions like thalassemia, the RBCs are smaller and may show increased central pallor due to reduced hemoglobin content.

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