Various factors can influence the appearance of central pallor:
Hemoglobin concentration: Lower levels of hemoglobin can lead to increased central pallor. Cell shape and size: Abnormalities in RBC shape (such as elliptocytosis) or size (such as microcytosis) can alter the appearance of central pallor. Staining technique: The quality and technique of staining can affect the visibility and assessment of central pallor.
