Several factors contribute to the development of degenerative lesions:
- Aging: The natural aging process leads to a gradual decline in cellular function and regenerative capacity. - Oxidative Stress: Excessive production of reactive oxygen species (ROS) can damage cellular components. - Inflammation: Chronic inflammation can promote tissue damage and fibrosis. - Genetic Factors: Mutations in certain genes may predispose individuals to degenerative diseases. - Environmental Factors: Exposure to toxins, radiation, and pathogens can accelerate tissue degeneration.
