White blood cells (WBCs) are classified into granulocytes (neutrophils, eosinophils, and basophils) and agranulocytes (lymphocytes and monocytes). Each type has distinct morphological features:
Neutrophils: Multi-lobed nucleus and granular cytoplasm. Eosinophils: Bi-lobed nucleus and large, red-staining granules. Basophils: Bi-lobed or S-shaped nucleus and dark blue-staining granules. Lymphocytes: Large, round nucleus with minimal cytoplasm. Monocytes: Kidney-shaped nucleus with abundant cytoplasm.
Changes in the number and morphology of WBCs are important in diagnosing infections, inflammations, and hematological malignancies.