There are three isoforms of SREBPs: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1a and SREBP-1c are products of the same gene but differ due to alternative splicing. SREBP-1c is primarily involved in the regulation of fatty acid synthesis, whereas SREBP-2 predominantly regulates cholesterol synthesis. SREBP-1a has a broader role and can regulate both fatty acid and cholesterol biosynthesis.
