myeloproliferative disorder

What Are the Treatment Options for Myeloproliferative Disorders?


Treatment varies based on the specific MPD and its severity. Options include:
Phlebotomy: Commonly used in polycythemia vera to reduce red cell mass.
Cytoreductive therapy: Medications like hydroxyurea are used to reduce cell proliferation.
Targeted therapy: In CML, tyrosine kinase inhibitors like imatinib target the BCR-ABL fusion protein.
JAK inhibitors: Ruxolitinib is used in diseases with JAK2 mutations.
Bone marrow transplantation: Considered for severe cases or those not responding to medication.

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