What Are the Treatment Options for Myeloproliferative Disorders?
Treatment varies based on the specific MPD and its severity. Options include:
Phlebotomy: Commonly used in polycythemia vera to reduce red cell mass. Cytoreductive therapy: Medications like hydroxyurea are used to reduce cell proliferation. Targeted therapy: In CML, tyrosine kinase inhibitors like imatinib target the BCR-ABL fusion protein. JAK inhibitors: Ruxolitinib is used in diseases with JAK2 mutations. Bone marrow transplantation: Considered for severe cases or those not responding to medication.