What Are the Complications of Myeloproliferative Disorders?
Complications can include:
Thrombosis: Increased risk in polycythemia vera and essential thrombocythemia. Hemorrhage: Abnormal platelet function can lead to bleeding complications. Transformation to Acute Leukemia: MPDs can progress to acute myeloid leukemia (AML), particularly primary myelofibrosis. Bone Marrow Fibrosis: Progressive fibrosis in primary myelofibrosis can lead to bone marrow failure.
