What are the Therapeutic Implications of p53 in Cancer Treatment?
Given its central role in tumor suppression, p53 is a target for various cancer therapies. Strategies to restore p53 function include gene therapy to introduce wild-type TP53, small molecules that reactivate mutant p53, and drugs that inhibit MDM2 to enhance p53 stability. Understanding the status of p53 in tumors can guide personalized treatment approaches and improve patient outcomes.
