What are the therapeutic approaches for Col4a4-related diseases?
Current therapeutic approaches for Col4a4-related diseases like Alport Syndrome focus on managing symptoms and slowing disease progression. Angiotensin-Converting Enzyme (ACE) Inhibitors and Angiotensin II Receptor Blockers (ARBs) are commonly used to reduce proteinuria and protect kidney function. Research is ongoing into more targeted therapies, including gene therapy and the use of stem cells to repair or replace defective basement membrane components. Early diagnosis and regular monitoring are crucial for managing these conditions effectively.
