What Are the Techniques Used to Study Genetic Diversity in Histology?
Several advanced techniques are employed to study genetic diversity in histology:
1. Immunohistochemistry (IHC): This technique uses antibodies to detect specific proteins in tissues. Variations in protein expression due to genetic diversity can be studied using IHC. 2. Fluorescence In Situ Hybridization (FISH): FISH is used to detect and localize the presence or absence of specific DNA sequences on chromosomes. It's useful for identifying genetic abnormalities in tissues. 3. Next-Generation Sequencing (NGS): NGS allows for the comprehensive analysis of genetic information. When combined with histology, it provides insights into how genetic variations affect tissue structure and function.