What are the Structural Characteristics of CD8+ T Cells?
In histological examinations, CD8+ T cells can be identified via immunohistochemistry using antibodies against the CD8 marker. They are relatively small cells with a high nucleus-to-cytoplasm ratio. The nucleus is dense and typically round or slightly indented. In tissue sections, CD8+ T cells are often found in close proximity to the cells they are targeting, especially in regions of active immune response such as lymph nodes and inflamed tissues.