What are the Sources of Physical Strain in Histology?
Several procedures in histology can introduce physical strain:
1. Tissue Fixation: Inadequate fixation can lead to tissue shrinkage and hardening. 2. Sectioning: Using a microtome to cut thin sections can cause compression or tearing. 3. Mounting: Stretching tissues onto slides can distort their natural structure. 4. Staining: Aggressive washing or drying steps can physically stress the tissue.
