What are the Limitations of Pulmonary Function Tests and Histology?
While PFTs provide functional data and histology offers structural insights, both have limitations. PFTs may not always correlate perfectly with symptoms or disease severity due to their dependence on patient effort and technique. Histology, on the other hand, involves invasive procedures like lung biopsies, which carry risks and may not always be feasible. Moreover, histological samples may not represent the entire lung pathology due to sampling errors.
