What are the Roles of Hormones in Bone Metabolism?
Several hormones regulate bone metabolism:
Parathyroid Hormone (PTH): Increases blood calcium levels by stimulating osteoclast activity and enhancing calcium absorption in the kidneys and intestines. Calcitonin: Lowers blood calcium levels by inhibiting osteoclast activity. Vitamin D: Promotes calcium absorption in the intestines and is crucial for bone mineralization. Growth Hormone: Stimulates bone growth by promoting the proliferation of osteoblasts and enhancing the production of bone matrix. Sex Hormones: Estrogen and testosterone play significant roles in maintaining bone density. They inhibit bone resorption and promote bone formation.