What are the Pathological Implications of Dysregulated Caveolin Mediated Endocytosis?
Dysregulation of caveolin-mediated endocytosis has been implicated in various diseases including: - Cancer: Altered caveolin expression can affect cell signaling pathways involved in tumor growth and metastasis. - Cardiovascular Diseases: Abnormal caveolae function can contribute to endothelial dysfunction and atherosclerosis. - Muscular Dystrophies: Mutations in caveolin-3 are associated with certain types of muscular dystrophies.