What are the Key Proteins Involved in Dense Fibrillar Components?
Several key proteins are localized within the DFC and are essential for its function. Fibrillarin is one of the most well-known nucleolar proteins and is involved in the methylation of rRNA. Nucleolin is another important protein that participates in pre-rRNA cleavage and modification. These proteins, along with others such as Nop56 and Nop58, form small nucleolar ribonucleoprotein particles (snoRNPs) that are critical for rRNA processing within the DFC.
