Several markers are commonly used to identify proliferating cells:
1. Ki-67: This protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but absent in resting cells (G0). It is widely used in both research and clinical settings to assess cell proliferation.
2. PCNA (Proliferating Cell Nuclear Antigen): PCNA is involved in DNA replication and repair. It is another popular marker for detecting proliferating cells.
3. BrdU: As mentioned, BrdU incorporation is a direct method for identifying cells undergoing DNA synthesis.
