What Are the Implications of These Histological Changes?
The histological changes in DMD have significant implications for muscle function:
Loss of Muscle Function: The replacement of muscle fibers with connective and fatty tissues leads to a loss of muscle function. Increased Susceptibility to Injury: The lack of dystrophin makes muscle cells more susceptible to damage during contraction and relaxation cycles. Impaired Regeneration: The regenerative capacity of muscle is impaired, leading to progressive muscle weakness.
