What are the Implications of Gliotransmitters in Neurological Disorders?
Dysregulated gliotransmitter release and signaling have been implicated in various neurological disorders. For instance, excessive glutamate release from astrocytes can contribute to excitotoxicity, a key feature in disorders like Alzheimer's disease and Amyotrophic lateral sclerosis (ALS). Furthermore, altered ATP signaling has been associated with chronic pain and migraine.
