What Are the Implications of Dysregulated Signal Transduction Pathways?
Aberrations in signal transduction pathways can lead to various diseases, including cancer, diabetes, and neurodegenerative disorders. For example, mutations in components of the MAPK/ERK pathway can result in uncontrolled cell proliferation, contributing to tumorigenesis. Similarly, defects in the PI3K/Akt pathway can lead to insulin resistance and metabolic syndrome.
