What Are Therapeutic Approaches Targeting Signal Transduction Pathways?
Many therapeutic strategies aim to modulate signal transduction pathways. These include:
1. Tyrosine Kinase Inhibitors (TKIs): Drugs that block the activity of RTKs, used in cancer treatment. 2. Monoclonal Antibodies: These target specific receptors or ligands to block signaling, such as anti-HER2 antibodies in breast cancer. 3. Small Molecule Inhibitors: These can inhibit key enzymes within pathways, such as MEK inhibitors in the MAPK/ERK pathway.
