What are the Histological Markers of Pulmonary Fibrosis?
Pulmonary fibrosis involves the accumulation of excess fibrous connective tissue in the lungs, leading to scarring and impaired gas exchange. The histological markers include:
Fibroblastic foci: Areas of active fibroblast proliferation. Dense collagen deposition replacing normal lung parenchyma. Honeycombing: Formation of cystic air spaces lined by bronchiolar epithelium. Loss of normal lung architecture and alveolar septa.
