Infected cells may show signs of apoptosis, characterized by cell shrinkage, chromatin condensation, and formation of apoptotic bodies. For example, _hepatocytes_ infected by the _Hepatitis C virus_ (another member of the Flaviviridae family) may display ballooning degeneration and lobular inflammation. Immunohistochemistry (IHC) can be used to detect viral antigens, aiding in the identification of infected cells.
