What are the Histological Features of Parafollicular Cells?
Histologically, parafollicular cells have several distinguishing features. They are polygonal or oval in shape with a large, centrally located nucleus. The cytoplasm of these cells is typically clear or pale due to the presence of secretory granules containing calcitonin. Electron microscopy reveals numerous dense-core secretory granules, which are indicative of their neuroendocrine nature.
