There are several key differences between B1 and B2 cells:
Origin: B1 cells originate from the fetal liver, while B2 cells develop from bone marrow progenitors. Surface Markers: B1 cells express CD5 and IgM, whereas B2 cells express CD19 and CD21. Function: B1 cells are involved in the production of natural antibodies and early immune responses, whereas B2 cells are primarily responsible for adaptive immunity.
