How Can Parafollicular Cells be Identified in Histological Sections?
Parafollicular cells can be identified in histological sections using specific stains and immunohistochemical markers. They are typically larger and paler than the surrounding follicular cells, with a more prominent nucleus. Immunohistochemical staining for calcitonin or the transcription factor TTF-1 (Thyroid Transcription Factor-1) can help highlight these cells. Silver stains and the Grimelius argyrophilic stain are also commonly used.
