Muscle degeneration can be caused by several factors:
1. Aging: Known as sarcopenia, age-related muscle loss is characterized by a decline in the number and size of muscle fibers. 2. Genetic Disorders: Conditions such as Duchenne Muscular Dystrophy are caused by genetic mutations that affect muscle protein function. 3. Inflammatory Myopathies: Conditions such as Polymyositis and Dermatomyositis involve chronic muscle inflammation leading to degeneration. 4. Neurogenic Atrophy: Damage to the nerves that supply muscles can lead to muscle atrophy. Conditions like Amyotrophic Lateral Sclerosis (ALS) fall under this category.