What are the Histological Features of Hypersegmentation?
Histologically, hypersegmented neutrophils are characterized by nuclei with more than five lobes. These cells can be easily identified on a stained peripheral blood smear. They often appear larger than normal neutrophils and may show cytoplasmic changes such as increased granularity. The presence of hypersegmented neutrophils is a key histological feature in diagnosing megaloblastic anemia and other related disorders.