What Are the Histological Changes in Sun-Damaged Skin?
Histologically, sun-damaged skin exhibits several changes: 1. Epidermal Thickening: Chronic sun exposure can cause the epidermis to thicken as a protective measure. 2. Solar Elastosis: There is an accumulation of abnormal elastic fibers in the dermis, giving the skin a yellowish and thickened appearance. 3. Keratinocyte Atypia: Abnormalities in keratinocytes, the predominant cell type in the epidermis, can lead to pre-cancerous conditions such as actinic keratosis. 4. Melanocyte Alterations: Changes in melanocyte activity can result in pigmentation disorders.
