gamma secretase

What are the Functions of Gamma Secretase?

Gamma secretase is involved in the cleavage of several key proteins, including the amyloid precursor protein (APP) and Notch receptors. The cleavage of APP by gamma secretase results in the production of amyloid-beta peptides, which are implicated in the pathogenesis of Alzheimer's disease. In contrast, the cleavage of Notch receptors is crucial for cell differentiation and developmental processes.

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