CD31 is involved in multiple biological functions: 1. Cell Adhesion: CD31 facilitates cell-to-cell adhesion, particularly between endothelial cells and circulating leukocytes. 2. Transmigration: It plays a pivotal role in the transmigration of leukocytes across the endothelium, a process critical for the immune response. 3. Signaling: CD31 is involved in intracellular signaling pathways that regulate cell survival, proliferation, and migration. 4. Angiogenesis: It contributes to the formation of new blood vessels, a process essential for tissue growth and repair.
