senescence associated secretory phenotype (sasp)

What are the Functional Implications of SASP?

SASP has both beneficial and detrimental effects:
1. Tissue Repair and Regeneration: In some contexts, SASP factors promote tissue repair by recruiting immune cells and stimulating tissue regeneration.
2. Inflammation and Aging: Chronic SASP can lead to sustained inflammation, contributing to chronic inflammatory diseases and tissue aging.
3. Cancer Promotion: SASP factors can create a pro-tumorigenic environment by promoting angiogenesis and altering the behavior of nearby cells.

Frequently asked queries:

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