The primary functions of PDGFRα include mediating responses to PDGF ligands, which are growth factors involved in various biological processes. These functions include:
Cell Proliferation: PDGFRα activation promotes the proliferation of cells, particularly during developmental stages and tissue repair. Cell Differentiation: It helps guide the differentiation of stem cells into specific cell types. Cell Migration: It plays a role in the directed movement of cells, which is essential for processes like wound healing and embryogenesis.
