What are the effects of Interferon Gamma on different tissues?
The effects of IFN-γ on various tissues can be profound:
- Immune Cells: Enhances the ability of macrophages to kill intracellular pathogens and activates T cells. - Epithelial Cells: Increases the expression of MHC class I and II molecules, improving antigen presentation. - Endothelial Cells: Promotes the expression of adhesion molecules, facilitating the migration of immune cells to infection sites.