Genomic instability can lead to a variety of outcomes, including:
- Cancer: One of the most significant consequences is the development of cancer. Mutations in genes that regulate cell growth and division, such as oncogenes and tumor suppressor genes, can lead to uncontrolled cell proliferation. - Aging: Genomic instability contributes to the aging process. Accumulation of DNA damage over time can lead to cellular senescence and loss of tissue function. - Genetic Disorders: Many genetic disorders are the result of genomic instability. For example, mutations in the DNA repair genes can lead to conditions like Xeroderma Pigmentosum and Lynch Syndrome.
