How Does SHG Compare to Traditional Staining Methods?
Traditional staining methods, such as Hematoxylin and Eosin (H&E) staining, rely on chemical dyes to provide contrast in tissue samples. While effective, these methods can sometimes obscure fine details or require extensive sample preparation. In contrast, SHG imaging is label-free and can provide high-resolution images of specific structures without altering the sample. Moreover, SHG allows for 3D imaging of tissues, providing more comprehensive information about tissue architecture.
