The consequences of chromosome breakage can range from benign to severe. Some potential outcomes include:
1. Genetic Mutations: Breakage and improper repair can lead to mutations, which may disrupt gene function. 2. Cancer: Unrepaired or misrepaired chromosome breaks can lead to oncogene activation or tumor suppressor gene inactivation. 3. Cell Death: Extensive chromosome damage can trigger cell death pathways such as apoptosis. 4. Genetic Disorders: Conditions like Fanconi anemia and Ataxia-telangiectasia are associated with high levels of chromosome breakage.
