NK cells have significant clinical implications in various diseases: - Cancer: NK cells are being explored for their potential use in cancer immunotherapy, such as adoptive NK cell transfer and NK cell-activating drugs. - Infections: Enhancing NK cell activity is a strategy being investigated in the context of viral infections, especially those caused by viruses that downregulate MHC class I molecules. - Autoimmune Diseases: Dysregulation of NK cell function is implicated in certain autoimmune conditions, making them a target for therapeutic intervention.
