NK cells perform several key functions, including: - Cytotoxic Activity: They can induce apoptosis in target cells through the release of cytotoxic granules containing perforin and granzymes. - Cytokine Production: NK cells secrete cytokines like IFN-γ and TNF-α which enhance the immune response by activating other immune cells such as macrophages and dendritic cells. - Regulation of Immune Response: By interacting with other immune cells, NK cells help regulate the overall immune response, ensuring it is effective yet controlled.