What are the Clinical Implications of Lysosomal Storage Disorders?
LSDs can manifest with a wide range of clinical symptoms depending on the specific disorder and organs involved. Common clinical features include:
- Neurological Symptoms: Such as developmental delay, seizures, and ataxia. - Organomegaly: Enlargement of organs like the spleen and liver. - Skeletal Abnormalities: Bone pain, deformities, and growth retardation. - Cardiovascular Issues: Heart disease and hypertension.
