What Are the Clinical Applications of Immunomodulation?
The clinical applications of immunomodulation are vast and varied: - Autoimmune Diseases: Immunosuppressants like corticosteroids and biologics are used to reduce the immune attack on the bodyâs own tissues, as seen in conditions like rheumatoid arthritis and lupus. - Organ Transplantation: Immunosuppressive drugs are crucial in preventing organ rejection post-transplantation by inhibiting the immune response against the transplanted organ. - Cancer: Immunostimulatory approaches, including checkpoint inhibitors and CAR-T cell therapy, are used to enhance the immune systemâs ability to recognize and kill cancer cells. - Chronic Infections: Immunostimulants can help in boosting the immune response to fight off persistent infections, such as those seen in HIV or hepatitis.
