What are the Challenges in Studying Circulating Fetal Cells?
Despite their potential, the study and utilization of circulating fetal cells face several challenges:
1. Low Abundance: Circulating fetal cells are rare, often constituting a very small fraction of the maternal blood cells. 2. Isolation and Purity: Isolating these few cells from a large volume of maternal blood while maintaining cell integrity and purity is technically challenging. 3. Technical Limitations: Advanced techniques are required to accurately identify and analyze these cells, making the process costly and complex.